Last year's runner-up Bengal made a mockery of a modest 236 run chase as Kerala's tidy bowling was backed up well by sharp fielding.
Bengal kept losing wickets at regular intervals to remain winless from two matches to slip to fifth spot in the seven- team group.
Bengal had lost their opening match to Maharashtra.
Opting to bat, opener Jalaj Saxena struck an unbeaten 100 off 133 balls (10x4s) to push Kerala's total to 235 for six in their group opener.
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Needing 36 runs from 42 balls with five wickets in hand, Bengal batsmen made a harakiri losing three wickets in 18 runs as Kerala managed to return with two points.
Debutant Sumanta Gupta, who toiled hard for his 23 of 27 in a 47-run partnership with Tiwary, departed in the 47th over, while Aamir Gani got out in space of five balls to make the task tougher.
Sandeep Warrier (2/38) and Abhishek Mohan (2/46) also bagged two wickets each as Tiwary was left frustrated in the middle.
Brief Scores:
Kerala 235/6; 50 overs (Jalaj Saxena 100 not out; Manoj Tiwary 2/23, Sayan Ghosh 2/56) tied with Bengal 235/8; 50 overs (Manoj Tiwary 73 not out, Sandeep Warrier 2/38, KC Akshay 2/45, Abhishek Mohan 2/46).
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