"I have taken hits before in politics, I am not worried about it," he told reporters at the State Department. "This is not about me."
Kerry said he is convinced that a humanitarian cease-fire in Gaza, followed by negotiations to resolve the underlying causes of the conflict, is "more appropriate" than continuing to wage war.
Kerry has come under harsh criticism in Israel and among its supporters for pushing a cease-fire last week that critics believe will hurt the security of the Jewish state and give legitimacy to the militant Hamas movement that controls Gaza.
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Though he said he wasn't "worried" by the criticism, Kerry showed flashes of anger in his comments, noting at one point that he had a 100-per cent pro-Israel voting record in the Senate and would not "take a second seat to anybody" in his devotion to Israel's security.
Kerry also said he would not be pushing for a cease-fire if Netanyahu hadn't asked him to. "Prime Minister Netanyahu himself said to me, 'Can you try to get a humanitarian cease-fire for this period of time?' And if it weren't for his commitment to it, obviously the president of the United States and I would not be trying to make this effort," Kerry said.