A source familiar with the matter said Emil Michael, a senior vice president reported to be close to chief executive Travis Kalanick, left the company.
Uber was bracing for more turmoil -- with some reports saying Kalanick himself may take a leave of absence -- with a report prepared by former US attorney general Eric Holder set to be given to employees tomorrow.
Uber's board met yesterday with Holder and consultant Tammy Albarran to discuss the findings and "unanimously voted to adopt all the recommendations" of the report, according to the source.
Uber also faces questions about its covert use of law enforcement-evading software and tactics apparently aimed at disrupting rivals in the ridesharing business.
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As part of the revamping at Uber, Nestle executive Wan Ling Martello was named as an independent board member, according to a source close to the company.
Michael had been linked to a number of questionable practices at Uber, media reports said, including a visit to a South Korean escort-karaoke bar and an attempt to dig up embarrassing information on journalists.
"It's safe to say that this week will be the week we finally learn just how committed Travis Kalanick and the rest of the senior leadership team at Uber is to meaningful cultural change," said Jan Dawson, an analyst with Jackdaw Research.
The report comes after a series of embarrassing revelations for the company over the past few months.
Last week, Uber said it had fired 20 people following preliminary results of the investigation, after examining 215 claims of discrimination, harassment, unprofessional behavior, bullying, retaliation and "physical security."
Last month, Uber fired executive Anthony Levandowski, who came from Google's self-driving car unit now known as Waymo, for failing to meet a deadline to turn over information for an internal investigation.
Waymo's lawsuit contends that Levandowski in December 2015 downloaded files from a highly confidential design server to a laptop and took the data with him to the startup.
Top engineering executive Amit Singhal resigned in February after the ride-sharing titan learned he ended his career at Google after a sexual harassment complaint, reports said.
The woes so far have not hit Uber's growth trajectory, but some analysts say its problems won't fixed without a change in leadership.
The privately-held firm is valued at about $68 billion, making it the largest "unicorn" or venture-backed startup.
Uber does not file full financial reports but indicated its bookings last year doubled to USD 20 billion, with net revenue totaling USD 6.5 billion and an adjusted net loss of USD 2.8 billion not counting China operations that it sold.
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