"Promise me, if something were to happen to me, you will take revenge from Nawaz Sharif," Khan said while addressing his supporters before starting his march towards the Red Zone that houses important government buildings including the Parliament House, Prime Minister House, President House, the Supreme Court besides embassies of various countries.
Unfazed by army deployment, the Pakistan Tehreek-i-Insaf chief and Qadri marched towards the Parliament demanding Prime Minister Nawaz Sharif's resignation, putting the PML-N-led government on the backfoot.
"PTI workers injured by Police baton charge ahead Serena chowk...Ambulance called there for first Aid," the PTI party said on twitter.
Anti-government protestors entered the Red Zone, even as clashes took place between them and the police at Serena Chowk where they removed shipping containers, Dunya TV reported.
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Police was not putting up stern resistance and slowly retreated as part of policy to avoid violence.
The protestors of Khan and Qadri started separately but later were moving towards the Parliament together.
Information minister Pervaiz Rashid told Geo TV that the marchers have violated written commitment that they will not enter the Red Zone.
Red alert was issued at capital's Polyclinic Hospital and Pakistan Institute of Medical Sciences (PIMS), the two leading state-run medical facilities. Arrangements for additional medicines, emergency operations and extra beds were also made at the two hospitals.
"I'm coming! I'm coming to hold you accountable!" Khan said, as his vehicle progressed towards the Red Zone.
Anti-government protesters were armed with wire cutters and cranes accompanied them to remove containers.
As the protesters marched towards the Parliament, Sharif was present inside the official residence in the 'Red Zone' along with senior leaders of his ruling PML-N party. He is personally keeping a tab on the developing situation.
Qadri was headed towards the Parliament in his bullet-proof car while Khan mounted on a truck with his party leaders.