Kardashian, 34, who welcomed daughter North West, 23 months, in June 2013, after a difficult delivery, reported Us magazine.
"Kim has been undergoing IVF. It's causing problems with her body," a source said.
Previously, the reality TV star had admitted that she was exhausted by her frequent attempts to get pregnant in the old fashioned way.
Kardashian, who recently got operated because some placenta was left in her uterus from her first pregnancy, commented that the doctor said it went well, and there was nothing more on this earth she wanted than to be pregnant again.