The 69-year-old leader, known for taking firm stand on several issues which led to differences between him and senior party colleagues, said he was sending his resignation letter to Congress President Sonia Gandhi today itself.
"My personal difficulties should not affect party work in any manner," Sudheeran, who was the choice of Congress Vice-President Rahul Gandhi for the post, told reporters here, announcing his sudden decision which took everyone by surprise.
He expressed hope that the AICC will make the necessary alternative arrangements.
Sudheeran had been keeping away from public functions due to ill health after he was recently injured while attending a function in Kozhikode.
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"I am indebted to the party for having reposed faith in me," Sudheeran said, adding "there is nothing political" in his decision to quit.
"The decision is purely due to personal inconvenience ant the party's interests are of paramount importance," he said.
He thanked party workers for the cooperation they had extended to him.
A proponent of prohibition, he had taken a firm stand against reopening over 700 closed Indian Made Foreign Liquor bars during the Oommen Chandy regime.
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Meanwhile, Chandy told reporters in Kochi that he would not succeed Sudheeran as KPCC chief in the state.
Chandy said there was no change in his stated position that he would not accept any official position.
"I have already stated that I will not accept any official post. There is no change in my stand," the senior Congress leader said.
(REOPEN MES2)
Congress sources said that following the mishap, Sudheeran had suffered injuries in his ribs and doctors had advised him a travel ban of one to two months.
Meanwhile, Sudheeran's sudden decision to resign took various Congress leaders in the state by surprise.
Veteran congress leader, A K Antony, said Sudheeran's resignation was 'very unfortunate.'
"This is certaintly a big loss to Kerala congress", he told reporters in Delhi.
Opposition leader in the state assembly, Ramesh Chennithala said the decision was 'totally unexpected'.
UDF Chairman P P Thankachan said the decision was only following health reasons and not due to any other reasons.