The "Keeping Up with the Kardashians" matriarch was booed when introducing Culture Club's performance at concert in Inglewood, California, reported Aceshowbiz.
Jenner, wearing a pantsuit and a matching hat, was barely heard due to the loud jeers as she talked about how she was inspired by the band and Boy George.
The TV star continued her speech, undeterred by the audience's lukewarm response.
Without mentioning the incident, Jenner wrote on Twitter, "Can't wait for @BoyGeorge... What a great night celebrating the 80's!!! #ifeelspecial #memories @theforum #bestvenue."