Seth W Owen has written the screenplay, which centres on a workaholic father (Simmons), who attempts to visit his daughter during a last-minute layover in Los Angeles only to discover that she's disappeared.
He is forced to team up with her awkward ex-boyfriend (Hirsch) to find her over the course of one night.
Schaal, 37, will play the high-strung, New Age-y woman who hosts the two men in her home, according to The Hollywood Reporter.
Gavin Wiesen ('The Art of Getting By') is directing the film.