The collection, which includes works by some of the greatest artists of the 20th century, goes under the hammer in New York, following a tour of Hong Kong, Paris, London and Los Angeles, reported CNN online.
Bacall, who died in August 2014 at the age of 89, first shot to international fame in 1944 with her first film "To Have And Have Not"
That was also when the husky-voiced starlet met her future husband, Humphrey Bogart.
At the recent 2015 Golden Globes, George Clooney paid tribute to the silver screen queen in his award winning speech.