The 39-year-old actor, who grew up in Los Angeles, said he was never swayed into the path of illegal substances, like many stars in the public eye, reported Contactmusic.
"I'd seen all the hedonism and insanity of the world of drugs. I grew up in a hardcore neighbourhood. Then coming to Hollywood and actually starting to make a career, you see the stuff around you and you're like, 'I saw this at age seven'. It's never really been a problem for me," DiCaprio said.
"I have done three films in two years. I am most certainly drained now. I will now take a long break before I come back," he said.