The event on August 23 is priced at USD 33,400-per-person and is billed as a "Conversation with Hillary", reported Variety.
The first USD 2,700 will go to the Clinton campaign, and the remainder will do to the Democratic National Committee and state and local parties.
Complete details are yet to be announced. Sources said plans were in the works for the event to take place at his home, but they were still being finalised.
DiCaprio, 41, attended a Clinton fundraiser at Harvey Weinstein's home in New York in June.