Tripoli residents are seething with anger over the violence that erupted Friday, particularly directed at powerful militias from the western city of Misrata operating in the capital.
The violence broke out when thousands of protesters marched on a neighborhood controlled by a number of powerful Misrata militias, prompting some militiamen to open fire, killing 43 people.
A day later, another militia attempted to overrun a military base, resulting in a clash with government forces that left four dead.
The Misrata city council also called on all armed groups, even those who are working under the government, to withdraw from the capital for a 72-hour period.
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In its statement, the Misrata city council held the government responsible for the security situation in Tripoli and for the safety of citizens originally from Misrata. There was no immediate government reaction to the decision.
Public anger had been directed at the militias from Misrata, who had developed a strong presence in the capital following the fall of longtime dictator Moammar Gadhafi in 2011.
Except for several protests, streets were deserted as the vast majority of Tripoli's businesses and schools were closed, with bakeries, pharmacies, hospitals and gas stations the main exception.
The head of Tripoli's city council, Al-Sadat al-Badri, said the strike is to last three days.
Yesterday, nearly a hundred protesters entered the parliament building while lawmakers were in session, demanding legislation to disband the militias and forcing the session to break up.