An international team of researchers performed a detailed analysis of organic carbon traces from the meteorite, and concluded that they have a very probable biological origin.
"So far, there is no other theory that we find more compelling," said Philippe Gillet, director of The Ecole polytechnique federale de Lausanne's Earth and Planetary Sciences Laboratory in Switzerland.
Scientists argue that carbon could have been deposited into the fissures of the rock when it was still on Mars by the infiltration of fluid that was rich in organic matter.
Upon examination, the alien rock was found to have small fissures that were filled with carbon-containing matter.
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Several research teams have already shown that this component is organic in nature. But they are still debating where the carbon came from.
They established characteristics that unequivocally excluded a terrestrial origin, and showed that the carbon content were deposited in the Tissint's fissures before it left Mars.
The researchers challenged previously described views proposing that the carbon traces originated through the high-temperature crystallisation of magma.
These conclusions are supported by several intrinsic properties of the meteorite's carbon, eg its ratio of carbon-13 to carbon-12.
This was found to be significantly lower than the ratio of carbon-13 in the CO2 of Mars's atmosphere, previously measured by the Phoenix and Curiosity rovers.
Moreover, the difference between these ratios corresponds perfectly with what is observed on Earth between a piece of coal - which is biological in origin - and the carbon in the atmosphere.
However, they consider this scenario unlikely because such meteorites contain very low concentrations of organic matter.
"I'm completely open to the possibility that other studies might contradict our findings. However, our conclusions are such that they will rekindle the debate as to the possible existence of biological activity on Mars - at least in the past," Gillet added.
The finding was published in the journal Meteoritics and Planetary Sciences.