Kudrow and producer Michael Patrick King are in talks with HBO for a limited series revival to air in 2015 to celebrate the show's 10th anniversary, reported Deadline.
'The Comeback' originally aired for a single season on HBO in 2005, but earned Kudrow a Primetime Emmy Award nomination.
Kudrow appeared in the mockumentary as faded star Valerie Cherish, whose attempts at a television comeback were being documented in a reality show.
Malin Akerman, 'Twilight' star Kellan Lutz and '30 Rock' actor Maulik Pancholy were among the stars to receive early fame on 'The Comeback'.
Kudrow has had a busy schedule over the last year, appearing in both the Showtime series 'Web Therapy' and ABC's 'Scandal'.