The 'Charlie Countryman' filmmaker has exited the 'Olympus Has Fallen' sequel over creative differences six weeks before shooting begins, according to The Hollywood Reporter.
Aaron Eckhart, Gerard Butler and Morgan Freeman will return for the follow-up to the 2013 action hit.
Angela Bassett and Melissa Leo will also feature in the film.
'London Has Fallen' sees the US president (Eckhart), secret service agent (Butler) and speaker of the US House of Representatives (Freeman) attending the funeral of a British prime minister after his mysterious death.
The funeral becomes central to a plot to kill the world's most high-profile leaders.
Bond's exit is said to be amicable.
'London Has Fallen' will released on October 2015.