The Caparo Group chief blamed "inappropriate scare tactics" which led to the Brexit vote but said the democratic decision must be respected.
"I am of course a very strong European and would have liked Britain to remain in the EU. Unfortunately, and mainly due to inappropriate scare tactics, the country voted to leave," he said in a speech at the opening of a new engineering facility at University of Wolverhampton.
"Those who thought that alarming people was a good strategy are now calling for a second referendum. But the country has made a democratic decision and as a democrat I believe we should uphold that decision...Let us support their efforts in obtaining an outcome that is fair, reasonable and concluded as soon as possible."
"We believe that this investment in advanced new engineering facilities and courses will strengthen the region's engineering infrastructure," Lord Paul said.
Tracing his own journey as a businessman, the UK-based millionaire relived how he started out with a small loan to build a successful multinational operation with state-of-the-art manufacturing facilities across many countries.
"We must continue to enhance and promote innovation and innovative practices within and throughout our supply chain. Innovation is central to growth but it also helps companies to survive adverse changes in operating circumstances; to gain competitive advantage, and in some cases to become market leaders," he said.