Louisville, the largest city in the southern state of Kentucky and home to 600,000 people, will play host Thursday and Friday to the mass public celebration of the life of Ali, its most famous native son.
Ali, whose remarkable boxing career and civil rights activism made him one of the most indelible figures of the 20th century, died last week at age 74 after a decades-long battle with Parkinson's disease.
"This celebration for Muhammad will be a one-of-a-kind event for anywhere in the world (...) and for us," Louisville Mayor Greg Fischer said, calling on the city's residents to show the hospitality and compassion that Ali championed.
"Muhammad shook up the world and he showed everybody he was a world-class fighter and humanitarian, so now let's welcome the world."
The ceremonies will have three key moments: an Islamic prayer service open to all on Thursday, a long public funeral procession through the city on Friday, and a memorial service at a sports arena that same day.