Researchers from Sax Institute in Australia investigated the links between education and cardiovascular disease events - such as a heart attack or stroke - by following 267,153 men and women in the state of New South Wales aged over 45.
"The lower your education, the more likely you are to have a heart attack or a stroke - that is the disturbing but clear finding from our research," said Rosemary Korda from the Australian National University (ANU).
The risk was around two-thirds (70 per cent) higher among those with intermediate levels of education (non-university qualifications).
"Mid-age adults who had not completed high school were 50 per cent more likely to have a first stroke than those with a university degree; those with intermediate levels of education (non-university qualifications) were 20 per cent more likely," said Korda.
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A similar pattern of inequality existed between household income and cardiovascular disease events, said Korda.
"We know that a good education impacts long term health by influencing what type of job you have, where you live and what food choices you make," said Kerry Doyle from Heart Foundation New South Wales in Australia.
"This research provides an opportunity to further unpack the specific relationship between educational achievement and cardiovascular disease risk, and what can be done to reduce this risk," she said.
The study was published in the International Journal for Equity in Health.