The "Area Codes" hitmaker first unveiled plans for the new venture in 2012, after closing down his Asian fusion restaurant Straits Atlanta, after four years in business.
At the time, he announced Chicken + Beer would launch at the Hartsfield-Jackson Airport in Atlanta, Georgia and offer "comfort foods and craft beers using locally-grown ingredients".
Ludacris took to Instagram to reveal the place is ready for business as he gave followers a quick tour of the restaurant in a short video clip.
"It took me three years, but it's finally coming to fruition," he said in the footage.
"I've seen it come from my third album, triple platinum album, all the way to a restaurant. Concourse D, D-5. We open tomorrow, November 17th, in the busiest airport in the world, Hartsfield. I'm talking about great food, great drinks, great energy, and my employees are the best employees in the world."
Chicken + Beer welcomed its first customers and Ludacris was on site to greet hungry fans.