Perry, 50, got emotional as a touching video of Patricia's advocacy on behalf of her late sister played for the audience, reported Entertainment Tonight.
The "8 Seconds" star as well as Patricia both talked about the significance of Perry's decades-long friendship with Alexis.
"He and Lex were friends since they were kids and I remember many years ago, the height of the 90210 craze, they all said, 'Alexis Arquette is dating Luke. Luke is secretly gay,'" Patricia said.
"Look when you love somebody, you love them. Bottom line. And I loved Lex and Lex loved me, and I don't need to explain that to anybody. That's how love works, and that's what's so special about the message Patricia spreads," Perry said.
Alexis, an avid transgender activist, died in September due to complications related to HIV/AIDS. She was 47.