The stock tumbled 7.31 per cent to settle at Rs 1,137.95 on BSE. During the day, it dived 9.74 per cent to Rs 1,108 -- its 52-week low.
On NSE, shares of the company tanked 7.18 per cent to end at Rs 1,140.20.
The stock was the worst performer among the Sensex and Nifty components.
On the volume front, 5.11 lakh shares of the company were traded on BSE and over 83 lakh shares changed hands on NSE during the day.
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"The company for Q4 FY17, posted results much below expectations mainly on OPM and the net profit front," said Sarabjit Kour Nangra, VP Research Pharma, Angel Broking.
Lupin yesterday reported over 49 per cent dip in consolidated net profit to Rs 380.21 crore for the fourth quarter ended March, mainly on account of increase in expenses and impact of foreign exchange fluctuation.
The company had posted a net profit of Rs 747.88 crore in the corresponding quarter of previous fiscal.