The play, written by 'The Walking Dead's Danai Gurira, features an all-black, female cast and the 33-year-old actress said she found the story of five women, who during the Liberian civil war in 2003 are trapped by rebel commander, an important narrative.
"Eclipsed" has been nominated for six Tony Awards and has been garnering praise for the actress.
Writing for Lenna Dunham's Lenny Letter, Nyong'o said during her last round of press, she was asked "Why would such a big star choose to do such a small play?", which felt silly to her.
The actress said perhaps there is more value given to Hollywood roles but she was bothered by the way success is perceived in society.
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"I think as women, as women of color, as black women, too often we hear about what we 'need to do.' How we need to behave, what we need to wear, what's deemed as too much or not enough, the cultural politics of what society considers appropriate for us and for our lives.
Nyong'o says stars like Tilda Swinton, Cate Blanchett, and Viola Davis inspire her as they are "fearless" actresses and "Eclipsed" gave her a chance to explore this, which was more fulfilling than playing an inconsequential role in Hollywood.
"So often women of color are relegated to playing simple tropes: the sidekick, the best friend, the noble savage, or the clown. We are confined to being a simple and symbolic peripheral character - one who doesn't have her own journey or emotional landscape.