Electing to bat, the South Africans scored 156/5 in their allotted 20 overs with Trisha Chetty top-scoring with 35 and Lizelle Lee contributing an unbeaten 30 and then restricted Ireland to 89 for 9 on the back of Sune Luus' impressive figures of 5/8, the best in the history of Women's World T20.
Sune Luus ripped through the opposition batting order by triggering a batting collapse which saw Ireland lose seven wickets for the addition of just 25 runs to lose the Group A match at the M A Chidambaram Stadium.
With the win today, the South Africans, who had lost to Australia in their opening match, now have two points from as many matches while a winless Ireland are virtually knocked out of the tournament after their second consecutive defeat.
The South African innings was built largely upon the 41-run opening stand between Dane van Niekerk (20) and Trisha and the fifth wicket partnership of 42 runs forged between Lizelle and Dinesha Devnarain (24).
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Lee, who hit three fours and a six in her 24-ball unbeaten knock, gave the impetus to the South African innings towards the end.
Joyce's departure led to a dramatic batting collapse as Ireland ended at 89 for 9 from 64 for 2 in the 12th over to lose the match.
Brief Scores:
South Africa: 156 for 5 in 20 overs (Trisha Chetty 35, Lizelle Lee 30 not out; Kim Garth 2/26)