Under the agreement, teams from both companies will collaborate and work together for up to 3 years to leverage benefits of Ford's global reach and expertise and Mahindra's scale in India, the two companies said in a statement.
"Any further strategic cooperation between the two companies will be decided at the end of that period," they added.
The companies said their alliance would look at areas of potential cooperation including, "mobility programmes, connected vehicle projects, electrification and product development".
Mahindra & Mahindra Managing Director Pawan Goenka said: "Today's announcement builds on the foundation laid through our past partnership with Ford and will open opportunities for both of us."
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The two companies had a 50:50 joint venture -- Mahindra Ford India Ltd -- in the mid-90s when Ford re-entered India.
Goenka said accelerated rise of new technologies, sustainability policies and new models of urban shared mobility have triggered changes in the automotive industry globally.
Ford Executive Vice-President and President of Global Markets, Jim Farley said the company is committed to India and the alliance could help it deliver the best vehicles and services to customers while profitably growing in the world's fifth largest vehicle market.
"Our two companies have a long history of cooperation and mutual respect. The memorandum of understanding we have signed today with Mahindra will allow us to work together to take advantage of the changes coming in the auto industry," he added.