Malaysia has never won Olympic gold in any sport, and the mild-mannered Lee has struggled with the pressure of his nation's hopes, suffering crushing final defeats to China's Lin Dan in Beijing and London.
But Rio finds the 33-year-old back in a familiar position -- world number one, looking strong, and an Olympic favourite -- and he has made clear his obsession to bring home gold this time.
"I have to make the best preparation since this is my last Olympic Games."
Lee's trophy case is packed with virtually every piece of badminton silverware available, but no Olympic or world championship, failures that haunt him.
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In particular, those heart-breaking losses to long-time nemesis -- and close friend -- Lin of China in the thrilling 2008 and 2012 Olympic singles finals clearly wounded Lee, and after London many began writing his career epitaph.
Things would get worse.
- Gritty comeback -
Lee, then world number one, tested positive for a forbidden anti-inflammatory drug at the 2014 world championships.
Facing a two-year ban, he fretted bleakly that his Olympic dream was dead.
But badminton authorities eventually accepted his explanation that he took the drug inadvertently amid stem-cell treatment for a thigh injury.