The 38-year-old actress will potentially portray the movie's villain, 'a calculating head of a tech company that is behind the monsters', reported Variety.
If the deal gets finalised, Akerman will join the previously-announced cast including Naomie Harris, Joe Manganiello, Marley Shelton, P J Byrne, Jack Quaid, Matt Gerald, Breanne Hill and Jake Lacy.
Based on the 1980s arcade game of the same name, "Rampage" will feature monstrously transformed gorilla, crocodile and wolf, which later will wreak havoc on North American cities and landmarks.
Johnson will play the world's only hope of stopping the gigantuous monsters.
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