The incident occurred in the evening at Kothagadi in Vikarabad town, when two groups quarreled over some matter, said Vikarabad DSP M Narasimhalu.
During the scuffle, one M Chandraiah was hit on his head with a stick and died of head injuries, the police officer said.
The injured included two accused and Chandraiah's son.
"There was no motive. Nothing was intentional and it was not pre-planned, though one person lost his life in the quarrel," the police officer said.