While Mangaonkar could not avenge his recent defeat against Adrian Waller and went down to the English left-hander, Sandhu slumped to an identical 1-3 defeat to Egypt's world no. 20 Mazen Hesham at the CCI courts.
Mangaonkar, ranked 52nd in the world, had lost to the English player - world no. 26 - in the final of last week's NSCI Open, the first tournament of the 2015 JSW Indian Circuit, and fell to Waller for the second time in five days.
Later, 21-year-old Hesham defeated 26-year-old Sandhu - ranked 56th in the world - 5-11, 11-5, 11-8, 11-5 to further dilute the home country's challenge in the tournament.
Mangaonkar had his chances as he held game-balls at 10-8 in the opening game before Waller drew level and then won over extra points with a fore-court winner.
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Waller, who played a very tight game that kept Mangaonkar out of the middle from the start, continued to dominate in the second one. Mangaonkar, docked a point for racquet abuse, worked for openings but committed a spate of errors to drop it.
But Waller who was back on top for the fourth game, though, frustrated Mangaonkar at every turn to win the match.