The 40-year-old director said he is prepared that Spider-Man is going back to Marvel Universe, reported MTV.
"I'm really psyched that Spider-Man is going back to the Marvel universe, I'm really excited to see that incarnation," he said.
Tom Holland was recently cast as Spider-Man for the reboot to be directed by Jon Watts.
"Jon Watts is directing it, I knew him from the old music video days and he'd done some really fantastic music videos, so it's really exciting. It's sad a little bit to surrender that in a way - but it's as it must be, I guess," said Webb, who directed the previous two Spider-Man films.
"And there's a lot of different ways to interpret that character whether it's Miles Morales or Peter Parker or whomever. I'm really curious to see how that evolves," he added.