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Marine animals key to combat ageing: scientists

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Press Trust of India London
Last Updated : Jan 25 2013 | 5:33 AM IST

Researchers from the Queen Mary, University of London investigated the genes of marine creatures such as sea urchins and sea cucumbers, known as echinoderms.

They found the genes for "messenger molecules" known as peptides, which are released by cells and tell other cells in their bodies what to do.

"Probably the most exciting discovery from our research was finding genes encoding peptides that cause rapid stiffening or softening of collagen in the body wall of sea cucumbers," lead researcher, Professor Maurice Elphick, said.

"Although sea urchins and sea cucumbers may not look much like us, we are actually quite closely related to them. As we get older, changes in collagen cause wrinkling of our skin, so if we can find out how peptides cause the body wall of a sea cucumber to quickly become stiff or soft then our research might lead to new ways to keeping skin looking young and healthy," Elphick said in a statement.

The scientists analysed the DNA sequences of thousands of genes in the purple sea urchin Strongylocentrotus purpuratus and the edible sea cucumber Apostichopus japonicus and specifically searched for genes encoding peptide messenger molecules.

"We found that sea urchins have a peptide that is very similar to calcitonin, a hormone that regulates our bones to make sure that they remain strong," Elphick said.

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"So it will be fascinating to find out if calcitonin-type peptides have a similar sort of role in spiny-skinned creatures like sea urchins," Elphick added.

The study was published in the journals PLOS One and General and Comparative Endocrinology.

  

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First Published: Oct 02 2012 | 3:05 PM IST

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