Foreign capital outflows also affected the market sentiment.
The Sensex resumed lower at 25,565.44 and hovered in a wide range of 25,705.96 and 25,057.93 before ending the week at 25,228.50, showing a loss of 378.12 pts or 1.48 per cent.
The Sensex has dropped by 609.64 points or 2.36 per cent in two weeks.
The NSE 50-share Nifty also dropped by 116.35 points or 1.48 per cent to more than three week low at 7,733.45. It has also dropped by 165.85 or 2.10 per cent in two weeks.
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Investor sentiment was badly hit following heavy losses in Japanese shares, as exporters took a major hit from surging yen after BOJ took investors by surprise by deciding against fresh stimulus.
"Value buying efforts were capped by India's PMI figures released during the week, which showed manufacturing activity slowed sharply in April," Anand James Chief Market Strategist Geojit BNP Paribas Financial Services.
foreign institutional investors (FIIs) sold shares worth Rs 729.82 crore during the week as per Sebi's record including the provisional figure of May 06.
In the broader market, the BSE Mid-Cap index fell by 77.64 points or 0.70 per cent to settle at 10,965.28 and the BSE Small-Cap index shed 121.28 points or 1.10 per cent to settle at 10,899.31. The decline in both this index was lower than Sensex's decline in percentage terms.
Among the S&P, BSE sector and industry indices, Metal fell by 3.60 per cent, followed by Banking 3.01 pct, BSE-IT 2.54 pct, BSE-Teck 2.49 pct, BSE-PSU 2.49 pct, Realty 1.67 pct, Oil&Gas 1.28 pct, Auto 1.07 pct, FMCG 1.01 pct, Consumer durables 0.62 pct and Capital goods 0.39 pct.
Major loser was, Adaniports dropped 18.17 per cent to Rs 194.95 and was the top loser from the Sensex pack followed by ICICI Bank 7.80 pct, Dr Reddy 7.31 pct, Tata Steel 6.02 pct ONGC 4.41 pct, Wipro 3.81 pct, Tata Motors 2.48 pct, Infosys 2.43 pct, SBIN 2.41 pct, TCS 2.29 pct, Axis Bank 2.28 pct, Bajaj Auto 1.78 pct, BhartiAirtel 1.39 pct, Reliance 1.36 pct, HDFC Bank 1.19 pct and Hero Motoco 1.00 pct.
While GAIL rose by 6.75 per cent followed by Asian Paint 2.34 per cent and NTPC 0.90 per cent.