In the space of little more than a decade, the event has evolved from a haphazard collection of meaningless friendlies to becoming the most prominent pre-season tournament in the world, what organiser Charlie Stillitano describes as the "perfect marriage of football and commerce."
Manchester United, Juventus, Paris Saint-Germain, Roma and Tottenham Hotspur are all competing in the tournament which comprises 12 matches across 11 US cities.
It is the first meeting of the two giants of La Liga outside of Spain since 1982, when they played a largely forgotten fixture in Venezuela.
Stillitano told AFP the stateside "Clasico", which will take place at the home of the Miami Dolphins, is being marketed with the same kind of razzmatazz surrounding the NFL's annual Super Bowl party.
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"It is very unique, we are creating a village, we are having concerts, parties, legends games, sponsors activation," Stillitano said.
Stillitano declined to go into the details of the sums necessary to attract such high-profile participants to the tournament, which also includes fixtures in Asia and Australia.
"It varies from team to team," he said. "The teams are paid very well, I can't say how much ... In some cases, we are sharing some revenues with the teams, I can't go into details."
Financing for the tournament is generated through ticketing and a network of commercial partners, notably Dutch brewer Heineken, which also sponsors the UEFA Champions League.
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The tournament begins on July 19, when Paris Saint- Germain take on Roma in Detroit with the final US fixture playing out on July 30 with an all-Italian derby between Roma and Juventus in Foxborough, outside of Boston.
"Soccer as a business has really grown, these teams are able to exploit their brand here in the US, which maybe 20 years ago they couldn't do," Stillitano said. "They all have robust marketing departments. Soccer is actually now very popular here."
Since the first friendly match he organised in 2002 -- a meeting between Real Madrid and Roma -- Stillitano says he has seen a definite shift in the way the event is perceived.
Mourinho, who has brought Chelsea, Real Madrid and now United to the US for pre-season training camps, calls Stillitano "Mr Zero Mistakes".
"Because everything he did for me: Zero mistakes," Mourinho told Sports Illustrated. "The clubs I bring to the US with Charlie, when I leave, the clubs keep the relation."
Stillitano added: "In 2003 and 2004, teams really didn't want to do it. In their minds it was not a tournament, just a series of games to show off the team. It's very, very different with what is is now."
In future Stillitano is eyeing other lucrative markets for fixtures, with India, South America and the Middle East under consideration.
Stillitano meanwhile remains coy about the suggestion that the International Champions Cup might offer a glimpse of what a breakaway European Super League might look like.
A meeting last year in London involving top clubs and Relevent Sports, which is owned by US billionaire Stephen Ross, fuelled speculation that a breakaway competition was the ultimate goal.
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