Medicines containing less then 0.2 per cent of tetrahydrocannabinol (THC), the plant's main psychoactive ingredient, can now be prescribed by doctors and bought in pharmacies, the head of Macedonia's agency for medicines Marija Darkovska-Serafimovska told reporters.
"This will help a huge number of Macedonian citizens that are fighting serious illnesses and have a need for treatment with nature-based products," Darkovska-Serafimovska said.
The medicines are available to patients battling health problems linked with cancer, multiple sclerosis and epilepsy.
"This is not a replacement for medical treatment," Health Minister Nikola Todorov said after parliament passed in May the new law allowing the sales following months of public debate.
Also Read
Other marijuana use remains illegal under Macedonian law.
So far 13 European Union nations have legalised marijuana-derived medicines including Austria, Britain, France, Germany, Italy, the Netherlands and Spain.
Macedonia applied for EU membership in 2005 but has yet to open accession talks.