The 29-year-old actress, who filed divorce papers in the Los Angeles County Superior Court, cited "irreconcilable differences" as the reason of their separation, reported Ace Showbiz.
The former "Transformers" leading lady is seeking joint physical and legal custody of their two sons; Noah, 2 years old, and Bodhi, 18 months.
Fox listed the date of their separation as June 15 despite recent speculation that they quietly split six months ago.
They reportedly did not sign a prenuptial agreement before tying the knot in 2010. She has allegedly hired divorce lawyer Laura Wasser.
According to sources, "they fight about her career. He would prefer she focus on the family more than being obsessed with getting roles.