The 22-year-old singer Grammy-winning pop star will take the stage to perform her hit single "NO" at the May 22 gala, reported E! online.
The first single lifted from her sophomore album Thank You, "NO" reached No 3 on the Billboard Hot 100 last month.
She will join alongside major names like Rihanna, Ariana Grande, Justin Bieber, Gwen Stefani and Blake Shelton, Celine Dion, DNCE, Britney Spears, Pink, Demi Lovato and Shawn Mendes among others.
Ludacris and Ciara will host the evening.