A programme of events in the northern German city involving Trump and other spouses of political leaders has had to be severely curtailed because of the demonstrations.
"The Hamburg police could not give us clearance to leave (the residence)," Trump's spokeswoman Stephanie Grisham said.
Instead of a visit to a climate centre, the spouses will be treated to presentations by climate scientists at a Hamburg hotel.
The German news agency DPA reported that Trump, 47, was unable to join the others on a tour of Hamburg harbour earlier today.
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Protest actions resumed early today with activists torching cars, smashing windows and even firing flares at police helicopters and slashing tyres on the Canadian delegation's cars.
Small groups played cat and mouse with police blocking traffic and trying to stop leaders from reaching the summit venue.
There are currently 20,000 police officers on duty for the two-day summit that began Friday, backed by helicopters, water cannon trucks and surveillance drones.