The 56-year-old 'Working Girl' star attended Italy's Taormina Film Festival, with Banderas' name hidden from the tattoo with the help of make-up, reported Us magazine.
The last time Griffith's tattoo had been seen intact was a day before she and Banderas made the official statement they were planning to end their relationship.
The trademark heart-shaped tattoo, which she first showed off in 1998, had a blurred, flesh-colored patch where the name "Antonio" was written.