This marks the 66-year-old actress' first-ever festival jury duty, said The Hollywood Reporter.
"It will be the first time in her longstanding career that this world famous star takes on the role of a juror at a film festival," the festival said.
Streep called the responsibility "daunting" but added she is grateful for the honour.
"It is a thrill to return to the festival under any circumstances, but it is with great relish and anticipation I look forward to jury duty," she said.
"The responsibility is somewhat daunting, as I have never been president of anything before, and I hope I can come up to the precedent set by the distinguished juries of preceding years. Grateful for the honour."
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In 1999, she was awarded the Berlinale Camera, and in 2003, together with Julianne Moore and Nicole Kidman, she shared the Silver Bear award for their performances in The Hours.
In 2006, she was in the Berlin festival competition in Robert Altman's ensemble comedy "A Prairie Home Companion". In 2012, she received the lifetime achievement honour.
"Meryl Streep is one of the most creative and multifaceted film artists. To mark our enthusiasm for her extraordinary talent we awarded her the honorary Golden Bear in 2012 for her lifetime achievement," said Berlinale director Dieter Kosslick.