Arizona border protection agents discovered millions of dollars worth of marijuana disguised in packages painted to look like watermelons, Fox News reported.
US Customs and Border Protection made the fruity find late on Thursday, it said.
Agents said they stopped a truck just outside of Tucson. The trailer had already made it across the border 32 km south and was stopping at a second checkpoint further into the US.
The driver said he was just hauling a load of watermelons.
The Drug Enforcement Agency is still working to determine the exact value of the haul, but officials estimated the load was worth millions.
The driver is still in custody, the report said.