Hendrik (Henk) Palm, from the northern Dutch town of Roden, died "after the indescribable grief of losing his daughter, Erla (Palm), son-in-law Rob (van der Linde) and grandchildren Merel and Mark" in the Malaysia Airlines crash, family members said in a death notice carried by De Stentor regional newspaper.
The notice, to be found on a link from the paper's website, said Palm died Tuesday, five days after the crash that claimed the lives of 298 people including 193 Dutch citizens.
Dutch newspapers have reported that the four, also from Roden, were on their way to Malaysia for a holiday.
Granddaughter Merel was 17, and her brother Mark, 12.
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Erla Palm had been the infirm, elderly widower's only daughter and key caregiver, her cousin told regional broadcaster RTV Drenthe.
Several people posted online condolences today in sympathy with the family tragedy.
"Dear Mr Palm, that you had to die of a broken heart. But hopefully you have now been reunited with your daughter," wrote one, who signed off as "A mother".
Most of the bodies have since arrived in the Netherlands for identification and forensic examination.