The 38-year-old actor earlier collaborated with Scott for the 2013 crime thriller "The Counselor" and the directed said "Prometheus 2", which is slated to begin production in February 2016, will be his next project, reported Aceshowbiz.
"Fassbender will do this one with me, and it's meant to start production in February. I'm in prep, now. I'll either shoot in Aussie, or here," Scott said.
The "Alien" director said the next "Prometheus" movie would be closely connected to the first film.
Scott's upcoming film is Matt Damon-starrer science fiction "The Martian", scheduled to release on October 2.