The 55-year-old actress had been offered the chance to play Clarence Starling in the Oscar-winning horror 'Silence Of The Lambs', which stars Anthony Hopkins as a cannibalistic serial killer, but she snubbed the role and it was later given to Jodie Frost, reported Contactmusic.
Looking back, Pfeiffer thinks it was a shame that she hasn't had another opportunity to work with the film's director, as she explained, "I haven't been able to work with Jonathan Demme since 'Married to The Mob'."
"I don't have an innate commercial nous. I'm always wrong," she said.