The big China debut pushed the movie's international gross to USD 748 million, reported Ace Showbiz.
With the US total of USD 332 million, the Universal film, which is a prequel/spin-off to the "Despicable Me" franchise, raked in a total of USD 1.08 billion worldwide.
Disney's "Toy Story 3" previously held the second position at USD 1.06 billion.
"Frozen (2013)" is still holding strong to its top position with USD 1.28 billion.
"Minions" will add to its number when it opens in Greece on September 24.
The studio has a fruitful year thanks to "Jurassic World", "Furious 7", "Straight Outta Compton", "Pitch Perfect 2", and "Fifty Shades of Grey".