Besides, the expiry of October series contracts in the derivatives segment tomorrow, influenced market sentiments.
The CNX 50-share Nifty also dropped 61.70 points, or 0.75 per cent, to close at 8,171.20.
"The negative bias prevailed for third day in a row, as a result, benchmarks slipped further in red and lost over half a per cent.
The Sensex resumed lower at 27,131.71 and hovered in a range of 27,163.98 and 26,919.96 before ending at nearly 2-week low of 27,039.76, showing a loss of 213.68 points or 0.78 per cent.
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The gauge has dropped 431.05 points or 1.57 per cent, in two days.
Among major losers, Axis Bank tumbled by 7.36 per cent on concerns over the private sector lender's slippages in the second quarter ended September 30, 2015.