The 31-year-old "Pop That" rapper will play music mogul Vaughn, a member of Lucious Lyon's powerful inner circle, and Birdman, 47, will appear as himself, reported Entertainment Weekly.
Series co-creator Lee Daniels as well as Birdman took to Instagram accounts to share photos of the set hanging out with lead actor Terrence Howard.
The second season of "Empire" ended with Rhonda and Anika fighting on the edge of a balcony and one of them apparently falling.
In May, show runner Ilene Chaiken confirmed the news of the death of one of the person but didn't reveal the name.