That changed Wednesday for 205 abandoned canines that arrived on the US mainland in an airlift organised by animal welfare advocates working to ease the load.
"The shelters in Puerto Rico have no choice," said Kimberly Alboum, director of policy engagement and shelter outreach for the Humane Society of the United States. "They run out of room and, unfortunately, they have to euthanize for space. It's heartbreaking for the staff and it's devastating because these animals are all highly adoptable."
It's common to see packs of what locals refer to as "satos" roaming through Puerto Rican communities, and one stretch of coast near the town of Yabucoa became so infamous for abandoned and abused pets that it was dubbed Dead Dog Beach.
Activists in Puerto Rico and on the mainland have been working on the problem and say there are signs of improvement.
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Christina Beckles, founder of the Puerto Rico-based Sato Project, said fewer dogs are ending up on Dead Dog Beach thanks in part to a campaign to spay and neuter in Yabucoa.
"People are leaving the island in droves because they can't afford to live here," Beckles said. "I would never condone someone abandoning an animal, but I understand."
While various organisations have airlifted dogs out of Puerto Rico in recent years, this latest effort is believed to be the largest number in a single trip.
Many of the animals came from two shelters: One in the hills above Mayaguez that has a hard time finding people to adopt its animals because it is so remote, and another in a condemned building with no power or water near Cabo Rojo that had to clear its entire population for a badly needed renovation.
The dogs were checked by veterinarians, taken to the San Juan airport and then flown in two planes provided by a group called Wings of Rescue.
They landed in Fort Lauderdale, Florida, dogs peeking nervously out of their carriers as volunteers unloaded them and transferred them to waiting vans. One planeload of dogs was destined for shelters around the state.
About two dozen ended up at a facility run by the Humane Society of Broward County in Fort Lauderdale.
"They'll all get adopted," shelter director Mary Steffen said. "They will go fast.