The No. 1 and 2 Chinese players, who are seeded fourth with direct entry in the main draw, won 11-7, 11-7, 11-1, 11-3 to enter the semifinals.
Manika and Mouma had become the first Indian doubles pair to reach last eight after getting a walkover in the round of 16.
"We did our best and are elated to have entered the quarterfinals. We got a bit lucky yesterday but combined really well to reach this important stage," said Mouma, who with 16 appearances is the first Asian to register most number of appearances in at World Championships.
Later tonight, Sharath Kamal is slated to play Chinese Lin Gaoyuan, who is ranked 40 in the world and seeded 33, in the round of 32. Sharath, the lone Indian left in fray and ranked 54, is seeded 43.
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