Mumbai restricted Madhya Pradesh to 214 in 45.1 overs but themselves fell for a meagre 134 in 38.4 overs.
Put in to bat, Madhya Pradesh opener Ankit Dane (46) and Sohraab Dhaliwal (51) chipped in with important contributions to take the team past 200-run mark.
For Mumbai, Shardul Thakur (3/27) was the pick of the bowlers with three scalps.
In reply, Mumbai kept losing wickets at regular interval with Sakure and Saransh Jain (3/30) doing the damage, sharing eight wickets between them.
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Brief scores:
Madhya Pradesh: 214 all out in 45.1 overs (Sohraab Dhaliwal 51, Ankit Dane 46; Shardul Thakur 3/27).
Mumbai: 134 all out in 38.4 overs (Abhishek Nayar 24; Chandrakant Sakure 5/25, Saransh Jain 3/30).
Summarised scores for other Group C matches:
1) Bengal beat Goa by 8 wickets
Goa: 213 for 9 in 50 overs (Amogh Desai 49, Kanishk Seth 3/50).
Bengal: 214 for 2 in 35.5 overs (Manoj Tiwary 116 not out, Abhimanyu Easwaran 68 not out).
2) Rajasthan beat Gujarat by 14 runs
Rajasthan: 183 all out in 47.0 overs (Arjit Gupta 69, Kamlesh Nagarkoti 56 not out).