The victims were on their way to Omkarreshwar for a pilgrimage when the mishap took place around 12 noon on Indore-Icchapur State Highway.
All of them are related to each other and belong to Pune and Bhusawal (Maharashtra), Khandwa SP, Manoj Sharma said.
Among the deceased, three are men along with as many women besides two children, police said.
The victims have not been identified yet. Further details are awaited.