He will report to Mullen Lowe Group Global CEO Alex Leikikh, the company said in a statement.
George has been with the Lowe network for 24 years, joining Lintas Mumbai in 1991.
"He is exactly the leader we need as part of our hugely dynamic Asia operation, he is a seasoned professional with a proven track record of growth. A key component of his role will focus on tapping into the resources of the robust India operation that he has built up in order to develop our hyperbundled offering across the Southeast Asia markets," Leikikh said.